C3ta12108a 10836..10846

نویسندگان

  • Baghali G. Mathapa
  • Vesselin N. Paunov
چکیده

We investigated the self-assembly of cyclodextrin (CD) molecules at the tetradecane–aqueous solution interface through formation of inclusion complexes (ICs). We studied the surface activity of CDs at both the air–water and the oil–water interface. Although a-CD and b-CD are not surface active at the air–water interface, they form pseudo-surfactants as inclusion complexes with linear oil molecules at the oil–water interface. We discussed the factors affecting the formation of these ICs and their assembly into microcrystals at the oil–water interface. We discovered that the morphology and the size of the aggregates formed by these ICs are dependent on the type of CD and oil used. Lamella sheets and long microrods were obtained from a-CD molecules and tetradecane. In contrast, b-CD–tetradecane gave short microrods which assembled in microcrystals. We characterised the CD–tetradecane ICs using optical microscopy, SEM, TEM and FT-IR. The crystallinity of the ICs was assessed using cross-polarised light microscopy. We demonstrated the spontaneous formation of a dense layer of adsorbed CD–tetradecane IC microcrystals at the tetradecane–water interface. At large oil volume fractions, this phenomenon led to the formation of a Pickering type of oil-in-water emulsion stabilised by adsorbed CD–oil microcrystals while at low oil volume fractions it completely solubilises the oil in the form of IC microcrystals. This emulsion stabilisation mechanism with sustainable materials like CDs may find applications in surfactant free pharmaceutical and cosmetic formulations reducing the release of surfactants in the environment.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Perception of Medical University Members From Nutritional Health in the Quran

BACKGROUND Desirable health is impossible without good nutrition, and Allah has addressed us on eating foods in 118 verses. OBJECTIVES This study aimed to describe the medical university faculty members' perceptions of nutritional health in the Quran, revealing the important role of faculty members. MATERIALS AND METHODS This qualitative study was conducted with a phenomenological approach....

متن کامل

XRCC1 Arg399Gln Polymorphism Confers Risk of Breast Cancer in American Population: A Meta-Analysis of 10846 Cases and 11723 Controls

BACKGROUND In the X-ray repair cross-complementing group 1 (XRCC1) gene, a polymorphism, Arg399Gln (rs25487), has been shown to change neoconservative amino acid and thus result in alternation of DNA repair capacity. Numerous studies have investigated the association between Arg399Gln and breast cancer risk in the American population, but yielding inconsistent results. This study aimed to clari...

متن کامل

Dihydromyricetin promotes autophagy and apoptosis through ROS-STAT3 signaling in head and neck squamous cell carcinoma

Chemotherapy is an effective weapon in the battle against cancer, but numerous cancer patients are either not sensitive to chemotherapy or develop drug resistance to current chemotherapy regimens. Therefore, an effective chemotherapy mechanism that enhances tumor sensitivity to chemotherapeutics is urgently needed. The aim of the present study was to determine the antitumor activity of dihydrom...

متن کامل

Ethacrynic acid improves the antitumor effects of irreversible epidermal growth factor receptor tyrosine kinase inhibitors in breast cancer

Prolonged treatment of breast cancer with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) often results in acquired resistance and a narrow therapeutic index. One strategy to improve the therapeutic effects of EGFR TKIs is to combine them with drugs used for other clinical indications. Ethacrynic acid (EA) is an FDA approved drug that may have antitumor effects and may...

متن کامل

The Role of Exposure to Phthalates from Polyvinyl Chloride Products in the Development of Asthma and Allergies: A Systematic Review and Meta-analysis

BACKGROUND Phthalates from polyvinyl chloride (PVC) plastics may have adverse effects on airways and immunologic systems, but the evidence has not been reviewed systematically. OBJECTIVE We reviewed the evidence for the role of exposure to phthalates from PVC products in the development of asthma and allergies. METHODS We conducted a Medline database search (1950 through May 2007) for relev...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013